2008年5月10日星期六

Cancer in developed countries has become one of the major causes of death2

Cancer is cancer, a disease. It is by controlling cell growth and proliferation mechanism of disorders caused by [1]. Apart from the uncontrolled growth of cancer cells, but also partially penetrated the surrounding normal tissue (infiltration, invasion) and even through the circulatory system or in the lymphatic system shifted to the other part of the body (long-distance transfers, metastasis). There are many types of cancer, and the severity of the disease depends on the location of the cancer cell growth and the degree of vicious, and whether there has been a long-range transfer. According to the doctors can check the Huotizuzhi biopsy (biopsy) or by operation in the organization, or even biological markers (biomarker) in a diagnosis. Most of cancer according to their type, in which the location and development stage can be treated and even cured. Once diagnosed, the cancer usually with surgery, chemotherapy and radiation therapy approach to treatment. With the progress of scientific research, the development of many specific types of cancer drugs, but also enhance the effectiveness of treatment. If the cancer untreated, is usually the end result will lead to death. Sustained growth of cancer cells without external control message may be the deactivation of the original cancer gene was activated, the cancer cells to import state, but mainly because the number of cell division and control the abnormal protein. Led to this situation, we may be the protein encoded by the DNA mutations and there were damaged, rendering the protein out of there so wrong. To a normal cell into a cancer cell mutation occurred in many needs, or the gene for the protein renders the process was interfered with. Gene mutation caused the material known as carcinogenic substances, and its genetic damage caused by the way can be divided into physical and chemical carcinogens and carcinogens. Such as contact with radioactive substances, or some environmental factor, such as cigarettes, radiation, alcohol. Some viruses can insert their own genes in the cells of genes, gene activation of carcinogens. But natural mutations would have, so even if the cancer to avoid contact with the above-mentioned factors, are still unable to completely prevent cancer from arising. A mutation in the germ cells may spread to the next generation. All ages who may have cancer, because of DNA damage with age and the cumulative increase in age by the greater the chance of cancer increases. U.S. annual death of five people which is one death from cancer, and the figure in the world is100-350 [2]. Cancer in developed countries has become one of the major causes of death.

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